Ncor1 CLIA Kit for Rat(Rattus norvegicus) | EIAab.comNcor1 CLIA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Ncor1(Gene name) > Rat

Ncor1 (Gene name),

Nuclear receptor corepressor 1 (Protein name ), NCOR1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ncor1;

Protein name:

Nuclear receptor corepressor 1(N-CoR;N-CoR1);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with C1D, SIAH2, HDAC7, SAP30, SIN3A and SIN3B. Interacts with CBFA2T3 and HEXIM1. Forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand. Interacts directly with RARA; the interaction is facilitated with RARA trimethylation. Interacts with DACH1. Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Interacts with TRIM28 and KDM3A. Interacts with ZBTB33; the interaction serves to recruit the N-CoR complex to promoter regions containing methylated CpG dinucleotides. Interacts (via the RD1 domain) with BAZ1A (via its N-terminal); the interaction corepresses a number of NCOR1-regulated genes.

Function:

Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

533

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

533:

ITQAAPHQQS | RIWEREPAPL | LSAQYETLSD | SDD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9WUB5

UniGene:

Rn.24948

Uniprot:

Q9WUB5

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ELISA Kit for Rat N-CoR

Cat.:

E0349h

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96T

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ELISA Kit for Rat N-CoR

Cat.:

E0349m

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96T

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ELISA Kit for Rat N-CoR

Cat.:

E0349r

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96T

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CLIA Kit for Rat N-CoR

Cat.:

U0349r

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Packing:

96T

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CLIA Kit for Rat N-CoR

Cat.:

U0349m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat N-CoR

Cat.:

U0349h

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Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Rat N-CoR

Cat.:

P0349Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat N-CoR

Cat.:

P0349Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat N-CoR

Cat.:

P0349Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat N-CoR

Protein for Rat N-CoR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin."
Boutell J.M. , Thomas P. , Neal J.W. , Weston V.J. , Duce J. , Harper P.S. , Jones A.L.
Hum. Mol. Genet.8:1647-1655(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"Effects of contractile activity and hypothyroidism on nuclear hormone receptor mRNA isoforms in rat skeletal muscle."
Schuler M.J. , Buehler S. , Pette D.
Eur. J. Biochem.264:982-988(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 476-528
tissue: Skeletal muscle.

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